Center on Macromolecular Dynamics by NMR Spectroscopy

The Center on Macromolecular Dynamics by NMR Spectroscopy (CoMD/NMR) is a Biomedical Technology Research Resource (BTRR) supported by U.S. National Institutes of Health grant P41 GM118302 and located at the New York Structural Biology Center (NYSBC). The mission of CoMD/NMR is to make available to the biological research community advanced NMR spectroscopic and computational methods for characterizing protein and nucleic acid conformational dynamics in biological processes.

Staff Technology Collaboration Education Dissemination

News and Events

CoMD/NMR is launched!

CoMD/NMR begins on June 1, 2017


New educational materials available: Tutorial on Model-free analysis of 15N relaxation data.


NMR Spectroscopy of Macromolecules to be taught at NYSBC, Spring 2018.

Recent Publications

Koss H Rance M, Palmer AG. General expressions for R relaxation for N-site chemical exchange and the special case of linear chains. J Magn Reson. 2017 Jan;274:36-45. doi: 10.1016/j.jmr.2016.10.015. PubMed PMID: 27866072; PubMed Central PMCID: PMC5199238.

Sergeyev IV, Itin B, Rogawski R, Day LA, McDermott AE. Efficient assignment and NMR analysis of an intact virus using sequential side-chain correlations and DNP sensitization. Proc Natl Acad Sci U S A. 2017 114:5171-5176. doi: 10.1073/pnas.1701484114. PubMed PMID: 28461483; PubMed Central PMCID: PMC5441803.